Adaptive Designs

boardwork

Study: Pediatric Leukemia

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Decide the Assignment

1. Form groups of 3
2. Copy the table onto the sheet of paper
3. Your task is to assign the next 6 patients to either treatment A or B, and then observe their outcomes. You can use any method you like, but you must write down your reasoning for each assignment.
4. Raise your hand to call us over to reveal a potential outcome.

\[ \begin{array}{c|c|c|c} \text{Patient} & d_i & y_i & \text{reason} \\ \hline 1 & A & 1 & random\\ 2 & B & 0 & random\\ 3 & A & 1 & random\\ 4 & B & 0 & random\\ 5 & ? & ? & ? \\ 6 & ? & ? & ? \\ 7 & ? & ? & ? \\ 8 & ? & ? & ? \\ 9 & ? & ? & ? \\ 10 & ? & ? & ? \\ \end{array} \]

Boardwork Debrief

\[ \begin{array}{c|c|c} \text{Patient} & Y_i(A) & Y_i(B) \\ \hline 1 & 1 & 0 \\ 2 & 1 & 0 \\ 3 & 1 & 1 \\ 4 & 0 & 0 \\ 5 & 0 & 1 \\ 6 & 0 & 1 \\ 7 & 1 & 0 \\ 8 & 0 & 1 \\ 9 & 0 & 1 \\ 10 & 1 & 1 \end{array} \]